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International Journal for Quality in Health Care Advance Access originally published online on September 1, 2006
International Journal for Quality in Health Care 2006 18(5):389; doi:10.1093/intqhc/mzl042
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International Journal for Quality in Health Care vol. 18 no. 5 © The Author 2006. Published by Oxford University Press on behalf of International Society for Quality in Health Care; all rights reserved

Letter to the Editor

Re: Reduction of broad-spectrum antibiotic use with computerized decision support in an intensive care unit

To the Editor: Investigators at the Royal Melbourne Hospital investigated effect of a computerized decision support tool on antibiotic use in an intensive care unit (ICU) in their adult surgical and medical ICU [1]. Undoubtedly, collation and clinical use of microbiology results and the individual prescriptions matching the patient’s infectious agents would result in better health care and the reduction of the total and broad-spectrum usage. In innumerable resource-poor developing countries, that would not be a reality in the near future. Inadequate laboratory and computer support apart, there is no restriction on the on-the-counter sale of antibiotics. Moreover, antibiotics prescriptions are the exclusive prerogative of the clinicians. Clinicians are obliged to prescribe antibiotics immediately in their ICU cases with a clinical picture indicating a possible bacterial infection. Without any prejudice to the clinical scenario, parenteral antibiotics are the universal choice.

In poor countries, local epidemiology and resistance profile, based on the retrospective analysis of the patient’s infectious agent should be a better standard than the generic guidelines [1]. That has been attempted in the Sant Parmanand Hospital, a private tertiary care hospital in the Indian capital metropolis. Retrospective antibiotic susceptibility profiles are recommended for selection of broader spectrum antibiotics in medical and surgical ICU. The profile is updated periodically and shared with clinicians charged with ICU patient management. There are frequent dialogues between clinical microbiology and the clinicians handling patients in ICU and patients with aggressive infections.

The impact of the local epidemiology and bacterial susceptibility profile awaits orderly evaluation. Constant updates on emergence of any isolates resistant to different antibiotics have been of interest among clinicians. There is no intrusion on the prerogative of any clinician to prescribe antibiotics of choice. There is no resentment towards acceptability of the local resistance profiles. Rather than the generic guidelines [1], the local approach has been a footstep towards the critical goal: a better quality management of patients in ICU.

Subhash C. Arya, Nirmala Agarwal and Shekhar Agarwal

Sant Parmanand Hospital, 18 Alipore Road, Delhi-110054, India

Acknowledgements

The technical assistance of Ms Kamini Singh and the secretarial assistance of Ms Sarita Kumar are acknowledged.

Reference

  1. Thursky KA, Buising KL, Bak N et al. Reduction of broad-spectrum antibiotic use with computerized decision support in an intensive care unit. Int J Qual Health Care 2006; 18 (3): 224–231.[Abstract/Free Full Text]


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This Article
Right arrow Extract Freely available
Right arrow FREE Full Text (PDF) Freely available
Right arrow All Versions of this Article:
18/5/389    most recent
mzl042v2
mzl042v1
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Right arrow Download to citation manager
Right arrowRequest Permissions
Google Scholar
Right arrow Articles by Arya, S. C.
Right arrow Articles by Agarwal, S.
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PubMed
Right arrow PubMed Citation
Right arrow Articles by Arya, S. C.
Right arrow Articles by Agarwal, S.
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